Topic Infection

Executive Summary

Periprosthetic joint infection in hip arthroplasty: is there an association between infection and bearing surface type

Authors:
Pitto RP., Sedel L.
Journal:
Clin Orthop Relat Res 2016; online June 2016. DOI 10.1007/s11999-016-4916-y
Level of Evidence:
Level III. Therapeutic study.

Summary

Pitto and Sedel aimed to assess whether the type of bearing surface (CoC, CoP, MoP, MoM) is associated with differences in risk of revision for early (<6 months) or late (>6 months) deep infection by using the national arthroplasty registry of New Zealand. In all they included 84,894 primary THA with a median observation period of 9 years. Included were only patients with degenerative joint disease without previous surgeries or trauma. There were 54,409 MoP, 16,503 CoP, 9,051 CoC and 4,931 MoM bearings. The following risk factors were included in the multivariate analysis: age, gender, operating room type, use of body exhaust suits, fixation mode, and surgeon volume.

During the first 6 months 0.07% CoC bearings, 0.09% CoP bearings, 0.15% MoP , and 0.14% MoM bearings were revised for infection. After controlling for certain confounding variables (see above), the authors did not find significant (<0.05) differences in risk of revision for deep infection within the first 6 months after surgery for the various bearing surfaces. The early rate of infection did not include surgical procedure for PJI that did not require exchange of components.

The overall revision rate for PJI of all bearings was 0.5% over the entire observation period (median 9 years). When the entire observation period was considered, CoC bearings were associated with a statistical significant lower risk of revision for infection (p=0.013) compared to CoP (HR, 1.3; CI, 0.78-2.18), MoP (HR, 2.21; CI, 1.23-3.65) and MoM (HR,1.75; CI,1.07-2.86) bearings. Kaplan-Meier survival analysis after 10 years showed no revisions for PJI in the CoC group but a constantly increasing revision rate for the other bearings.

Key Research Findings

Study limitations

The investigators did not stratify the analysis according to polyethylene quality.

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